职称/职务

讲师

导师类型

硕导

联系电话

15802879516

电子邮箱

jiaxuecao@sicau.edu.cn

研究方向

1.基因编辑技术

2.羊的重要经济性状研究

3.表观遗传学

学术、技术组织任职/头衔

四川省生物信息学学会会员

受教育及

工作经历

教育经历：

1.2014-09至2016-09,哈佛大学,人类进化生物系,联合培养博士,导师: Terence D Capellini

2.2011-09至2014-08,中国农业科学院北京畜牧兽医研究所,畜禽资源与遗传育种系,联合培养博士,导师:杜立新

3.2010-09至2016-12,古天乐代言太阳娱乐集团,古天乐代言太阳娱乐集团,博士,导师:张红平

4.2006-09至2010-06,古天乐代言太阳娱乐集团,古天乐代言太阳娱乐集团,学士

工作经历：

2017-01至现在,古天乐代言太阳娱乐集团,动物科学系,讲师

教学课程

《畜牧学通论》

人才培养情况

在读硕士研究生2人

科研项目

（近五年）

国家自然科学基金委员会，青年科学基金项目，31802048,NamiRNA-193b-3p靶向IGF2BP1调控山羊骨骼肌卫星细胞增殖分化的分子机制，2019-01至2021-12，23万元，在研，主持

代表性论文

(1) Daniel Richard; Zun Liu;Jiaxue Cao; Ata M Kiapour; Jessica Willen; Siddharth Yarlagadda; Evelyn Jagoda; Vijaya B. Kolachalama; Gary H. Chang; Jakob T. Sieker; Johannes Konrad; Pushpanathan Muthuirulan; Mariel Young; Anand Masson; David E. Maridas; Shayan Hosseinzadeh; Roman Krawetz; Vicki Rosen; Neil Roach; Terence D. Capellini. Evolutionary Selection and Constraint on Human Knee Chondrocyte Regulation Impacts Osteoarthritis Risk, CELL, 2020, Accepted.

(2) Steven K Pregizer ; Ata M Kiapour ; Mariel Young; Hao Chen; Michael Schoor; Zun Liu;Jiaxue Cao; Vicki Rosen; Terence D Capellini. Impact of broad regulatory regions on Gdf5 expression and function in knee development and susceptibility to osteoarthritis, Annals of the Rheumatic Diseases, 2018, 77(3)

(3) Terence D Capellini ; Hao Chen ;Jiaxue Cao; Andrew C Doxey; Ata, M Kiapour; Micheal Schoor; David M Kingsley. Ancient selection for derived alleles at a GDF5 enhancer influencing human growth and osteoarthritis risk, Nature Genetics, 2017, 49(8): 1202~1210

(4)Jiaxue Cao; Caihong Wei ; Shuzhen Zhang; Terence D Capellini; Li Zhang; Fuping Zhao; Li Li; Tao Zhong; Linjie Wang; Lixin Du ; Hongping Zhang. Screening of reproduction-related single-nucleotide variations from MeDIP-seq data in sheep, Molecular Reproduction and Development, 2016, 83(11): 958~967

(5) Caihong Wei ; Huihua Wang ; Gang Liu; Fuping Zhao; James W Kijas, Youji Ma; Jian Lu; Li Zhang;Jiaxue Cao; Mingming Wu; Guangkai Wang; Ruizao Liu; Zhen Liu; Shuzhen Zhang; Chousheng Liu ; Lixin Du. Genome-wide analysis reveals adaptation to high altitudes in Tibetan sheep, Scientific Reports, 2016, 6: e26770

（5）Mingming Wu ; Caihong Wei ; Zhengxing Lian; Ruizao Liu; Caiye Zhu, Huihua Wang;Jiaxue Cao; Yuelei Shen; Fuping Zhao; Li Zhang; Zhu Mu; Yayu Wang; Xiaogang Wang ; Lixin Du ; Chuduan Wang. Rosa26-targeted sheep gene knock-in via CRISPR-Cas9 system, Scientific Reports, 2016, 6: e24360

(7)Jiaxue Cao; Caihong Wei ; Dongming Liu; Huihua Wang; Mingming Wu; Zhiyuan Xie; Terence D Capellini; Li Zhang; Fuping Zhao; Li Li; Tao Zhong; Linjie Wang; Jian Lu; Ruizao Liu; Shifang Zhang; Yongfei Du; Hongping Zhang; Lixin Du. DNA methylation Landscape of body size variation in sheep Scientific Reports, 2015, 5: e13950

(8)曹家雪;张红平;杜立新.环境因素对DNA甲基化的影响遗传2013 35(7): 839~846

(9) Jian Lu ; Caihong Wei ; Xiaoning Zhang; Lingyang Xu; Shifang Zhang; Jiashen Liu;Jiaxue Cao; Fuping Zhao; Li Zhang; Bichun Li ; Lixin Du. The effect of myostatin silencing by lentiviral-mediated RNA interference on goat fetal fibroblasts, Molecular Biology Reports , 2013, 40(6): 4101~4108

(10)曹家雪;董恩妮;李利;李秋;张红平;王永;邓中宝;龚华斌.山羊胰岛素样生长因子结合蛋白1基因的生物信息学分析,中国畜牧兽医, 2012, 39(5): 56~62

各类获奖

专利、新品种、教材、专著等

社会服务

四川省科学技术厅，2019年度“三区”人才支持计划，南江黄羊育种规划、养殖生产技术咨询